Resource Type

Journal Article 48

Conference Videos 4

Year

2023 4

2022 5

2021 4

2020 1

2019 4

2018 1

2017 3

2016 2

2015 1

2014 5

2013 1

2012 3

2011 2

2010 4

2007 5

2006 2

2005 1

2004 1

2000 1

open ︾

Keywords

heat release rate 3

Controlled release 2

Nitrogen 2

Phosphorus 2

Sediment 2

combustion 2

controlled release 2

cytokine release syndrome 2

drug delivery 2

hematopoietic stem cell transplantation 2

phosphorus 2

5-Amino salicylic acid 1

Microcystis aeruginosa 1

Algicides 1

Aluminum-based P-inactivation agent 1

Anastrepha 1

Anastrephin 1

Biotoxicity 1

Black and odorous substances 1

open ︾

Search scope:

排序： Display mode:

Testing of tuberculosis infection among Chinese adolescents born after terminating the Bacillus Calmette--Guérin booster vaccination: subgroup analysis of a population-based cross-sectional study

Hengjing Li, Henan Xin, Shukun Qian, Xiangwei Li, Haoran Zhang, Mufei Li, Boxuan Feng, Qi Jin, Lei Gao

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 528-535 doi: 10.1007/s11684-017-0573-0

Abstract:

The prevalence of tuberculosis infection among adolescents born after terminating the Bacillus Calmette–Guérin (BCG) booster vaccination in China was estimated using tuberculin skin testing (TST) and QuantiFERON-TB Gold assay (QFT) to investigate the influence of neonatal BCG vaccination on the performance of TST. Data analysis was conducted for 2831 eligible participants aged 5–15 years from the baseline survey of a population-based multi-center prospective study. The prevalence rates of TST (induration≥10 mm) and QFT positivity were 9.3% (264/2827) and 2.5% (71/2831), respectively. The rate of QFT indeterminate result was 2.2% (62/2831). The overall agreement between TST and QFT was low (concordance= 88.0%; κ coefficient= 0.125). Only TST was positively associated with BCG vaccination with an adjusted odds ratio of 1.71 [95% confidence interval, 1.26–2.31]. A history of close contact with patients of active TB was significantly associated with positivity for TST and QFT. Our results suggested that BCG neonatal vaccination still affects TST performance, and a two-step approach might be considered for TB infection testing among adolescents in China.

Keywords： tuberculin skin test     interferon-γ release assays     adolescent     agreement    

HTML PDF Collect

High-expression of recombinant human concensus interferon-α by Pichia pastoris

HAO Yuyou, SHI Qiqi, HE Yun, ZHUANG Yingping, WANG Yonghong, ZHANG Siliang, CHU Ju, LIU Zhimin

Frontiers of Chemical Science and Engineering 2007, Volume 1, Issue 4,   Pages 399-403 doi: 10.1007/s11705-007-0073-x

Abstract: The present work focused on the high expression of recombinant human consensus interferon- (cIFN) by

Keywords： bioactivity     pastoris     maximum     induction     optimized    

HTML PDF Collect

Interferon-α salvage treatment is effective for patients with acute leukemia/myelodysplastic syndrome

Xiaodong Mo, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Wei Han, Fengrong Wang, Jingzhi Wang, Kaiyan Liu, Xiaojun Huang

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 238-249 doi: 10.1007/s11684-017-0599-3

Abstract: The efficacy of salvage interferon-α (IFN-α) treatment was investigated in patients with unsatisfactory

Keywords： interferon-α     hematopoietic stem cell transplantation     minimal residual disease     donor lymphocyte infusion    

HTML PDF Collect

Minimal residual disease-directed immunotherapy for high-risk myelodysplastic syndrome after allogeneic hematopoietic stem cell transplantation

Xiaodong Mo, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Wei Han, Fengrong Wang, Jingzhi Wang, Kaiyan Liu, Xiaojun Huang

Frontiers of Medicine 2019, Volume 13, Issue 3,   Pages 354-364 doi: 10.1007/s11684-018-0665-5

Abstract: The efficacy of minimal residual disease (MRD)-directed immunotherapy, including interferon- (IFN- )

Keywords： donor leukocyte infusion     hematopoietic stem cell transplantation     interferon-   

HTML PDF Collect

Phase separation in cGAS-STING signaling

Frontiers of Medicine   Pages 855-866 doi: 10.1007/s11684-023-1026-6

Abstract: Biomolecular condensates formed by phase separation are widespread and play critical roles in many physiological and pathological processes. cGAS-STING signaling functions to detect aberrant DNA signals to initiate anti-infection defense and antitumor immunity. At the same time, cGAS-STING signaling must be carefully regulated to maintain immune homeostasis. Interestingly, exciting recent studies have reported that biomolecular phase separation exists and plays important roles in different steps of cGAS-STING signaling, including cGAS condensates, STING condensates, and IRF3 condensates. In addition, several intracellular and extracellular factors have been proposed to modulate the condensates in cGAS-STING signaling. These studies reveal novel activation and regulation mechanisms of cGAS-STING signaling and provide new opportunities for drug discovery. Here, we summarize recent advances in the phase separation of cGAS-STING signaling and the development of potential drugs targeting these innate immune condensates.

Keywords： biomolecular condensates     phase separation     cGAS-STING pathway     cGAS     STING     cGAMP     interferon    

HTML PDF Collect

Design of nanocarriers for efficient cellular uptake and endosomal release of small molecule and nucleic

Vaibhav Mundra, Ram I. Mahato

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 4,   Pages 387-404 doi: 10.1007/s11705-014-1457-3

Abstract: Viruses exploit intracellular cues to release the genome to cytosol.

Keywords： nanocarrier     cellular uptake     endosomal release     nucleic acid drug    

HTML PDF Collect

Semi-solid materials for controlled release drug formulation: current status and future prospects

Michelle TRAN,Chun WANG

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 2,   Pages 225-232 doi: 10.1007/s11705-014-1429-7

Abstract: Here we review several common semi-solid polymers currently used in the controlled release formulations

Keywords： controlled release     drug delivery     semi-solids     polymer     excipient    

HTML PDF Collect

Study on the NOx release rule along the boiler during pulverized coal combustion

JIN Jing, ZHANG Zhongxiao, LI Ruiyang

Frontiers in Energy 2007, Volume 1, Issue 1,   Pages 91-95 doi: 10.1007/s11708-007-0009-7

Abstract: Numerical simulation and experimental study on NO release along the boiler during pulverized coal combustionWith the increase of temperature the NO emission increased and the peak value of NO release moved forwardThe peak value of NO release moved backwards with the increase of coal rank.
HTML PDF Collect

Capacity estimation and preliminary strategy for reducing the release of dioxins in China

YU Gang, ZHANG Qing, HUANG Jun, CAI Zhenxiao, SUI Qian

Frontiers of Environmental Science & Engineering 2007, Volume 1, Issue 1,   Pages 13-17 doi: 10.1007/s11783-007-0002-8

Abstract: The strategy and action plan for reducing the release of dioxins in China are the most important componentssources for applying the best available technology/best environmental practice (BAT/BEP) to reduce the releaseHow about the capacity for reducing the dioxins release from the key sources?The list of key sources covering about half of the total dioxins release was determined considering fourcorresponding to the scenario that all key sources have been applied BAT/BEP to reduce the dioxins release

Keywords： GIS     difference     capacity     scenario     implementation    

HTML PDF Collect

Synthesis and characterization of biocompatible polyurethanes for controlled release of hydrophobic and

Juichen YANG,Hong CHEN,Yuan YUAN,Debanjan SARKAR,Jie ZHENG

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 4,   Pages 498-510 doi: 10.1007/s11705-014-1451-9

Abstract: Design of biocompatible and biodegradable polymer systems for sustained and controlled release of bioactiveHere, we designed, synthesized, and characterized four polyurethane carrier systems for controlled releaseBy tuning polyurethane segments, different release profiles of hydrophobic and hydrophilic drugs wereSuch difference in release profiles was attributed to a complex interplay among structure, hydrophobicityan important role of segmental structure of the polyurethane as an engineering tool to control drug release

Keywords： phase structure     degradation     polyurethanes     controlled release     drug delivery    

HTML PDF Collect

functional supramolecular nanoparticles based on pillar[5]arene for controlled generation, storage and release

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 3,   Pages 307-313 doi: 10.1007/s11705-022-2216-5

Abstract: The storage and controlled release of singlet oxygen (1O2) have attracted increasinghydroxyphenyl)porphyrin (TPP), that may provide the controlled generation, storage and releaseinto one functional system, which provides a new strategy for the controlled generation, storage and release

Keywords： storage and controlled release of singlet oxygen     supramolecular nanoparticles     noncovalent interactions    

HTML PDF Collect

Phosphorus release potential and pollution characteristics of sediment in downstream Nansi Lake, China

Zhijian LI, Qinyan YUE, Baoyu GAO, Yanwen WANG, Qing LIU

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 2,   Pages 162-170 doi: 10.1007/s11783-011-0313-7

Abstract: to evaluate present and potential phosphorous pollution due to high sedimentary phosphorus load and releaseKinetics and isotherms of adsorption/release of sedimentary phosphorus were studied to determine equilibriumphosphate concentration (EPC ) and release potential.Kinetics of phosphorus adsorption on sediment and release from sediment were well described by both theimpermanent equilibrium with overlying water in status of phosphorus, the sediments can be likely to release

Keywords： Nansi Lake     sediment     phosphorus     release potential     equilibrium phosphate concentration    

HTML PDF Collect

Controlled drug release of 5-amino salicylic acid by poly(2-hydroxyethylmethacrylate) grafted agar

G. Usha RANI,Kartick Prasad DEY,Srijita BHARTI,Sumit MISHRA

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 4,   Pages 465-470 doi: 10.1007/s11705-014-1452-8

Abstract: utilization of poly (2-hydroxyethylmethacrylate) grafted agar (Ag-g-P(HEMA)) as a matrix for the controlled releasedrug release studies were performed at pH values of 2 and 7 in order to investigate the possibility ofpH triggered release for colon targeted drug delivery.it may be possible to develop a programmable drug release matrix based on grafted polysaccharide.Ag-g-P(HEMA) appears to be a useful matrix for controlled release.

Keywords： agar     controlled drug release     5-Amino salicylic acid     poly(2-hydroxyethylmethacrylate) grafted agar    

HTML PDF Collect

Four kinds of capping materials for controlling phosphorus and nitrogen release from contaminated sediment

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 3, doi: 10.1007/s11783-021-1463-x

Abstract:

• Lanthanum modified bentonite (LMB) can effectively absorb phosphorus (P).

Keywords： Sediment     Eutrophication     Thin-layer capping     Phosphorus     Nitrogen     Aluminum-based P-inactivation agent    

HTML PDF Collect

Effect of Fe on NO release during char combustion in air and O

Ying GU, Xiaowei LIU, Bo ZHAO, Minghou XU

Frontiers in Energy 2012, Volume 6, Issue 2,   Pages 200-206 doi: 10.1007/s11708-012-0181-2

Abstract: The chemistry of char was probed by studying nitrogen release under the reactions with air and oxy-fuelThe results also indicate that the release of NO increases more significantly with the Fe addition in

Keywords： NO     Fe     char     combustion     CO2    

HTML PDF Collect

Title Author Date Type Operation

Testing of tuberculosis infection among Chinese adolescents born after terminating the Bacillus Calmette--Guérin booster vaccination: subgroup analysis of a population-based cross-sectional study

Hengjing Li, Henan Xin, Shukun Qian, Xiangwei Li, Haoran Zhang, Mufei Li, Boxuan Feng, Qi Jin, Lei Gao

Journal Article

High-expression of recombinant human concensus interferon-α by Pichia pastoris

HAO Yuyou, SHI Qiqi, HE Yun, ZHUANG Yingping, WANG Yonghong, ZHANG Siliang, CHU Ju, LIU Zhimin

Journal Article

Interferon-α salvage treatment is effective for patients with acute leukemia/myelodysplastic syndrome

Xiaodong Mo, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Wei Han, Fengrong Wang, Jingzhi Wang, Kaiyan Liu, Xiaojun Huang

Journal Article

Minimal residual disease-directed immunotherapy for high-risk myelodysplastic syndrome after allogeneic hematopoietic stem cell transplantation

Xiaodong Mo, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Wei Han, Fengrong Wang, Jingzhi Wang, Kaiyan Liu, Xiaojun Huang

Journal Article

Phase separation in cGAS-STING signaling

Journal Article

Design of nanocarriers for efficient cellular uptake and endosomal release of small molecule and nucleic

Vaibhav Mundra, Ram I. Mahato

Journal Article

Semi-solid materials for controlled release drug formulation: current status and future prospects

Michelle TRAN,Chun WANG

Journal Article

Study on the NOx release rule along the boiler during pulverized coal combustion

JIN Jing, ZHANG Zhongxiao, LI Ruiyang

Journal Article

Capacity estimation and preliminary strategy for reducing the release of dioxins in China

YU Gang, ZHANG Qing, HUANG Jun, CAI Zhenxiao, SUI Qian

Journal Article

Synthesis and characterization of biocompatible polyurethanes for controlled release of hydrophobic and

Juichen YANG,Hong CHEN,Yuan YUAN,Debanjan SARKAR,Jie ZHENG

Journal Article

functional supramolecular nanoparticles based on pillar[5]arene for controlled generation, storage and release

Journal Article

Phosphorus release potential and pollution characteristics of sediment in downstream Nansi Lake, China

Zhijian LI, Qinyan YUE, Baoyu GAO, Yanwen WANG, Qing LIU

Journal Article

Controlled drug release of 5-amino salicylic acid by poly(2-hydroxyethylmethacrylate) grafted agar

G. Usha RANI,Kartick Prasad DEY,Srijita BHARTI,Sumit MISHRA

Journal Article

Four kinds of capping materials for controlling phosphorus and nitrogen release from contaminated sediment

Journal Article

Effect of Fe on NO release during char combustion in air and O

Ying GU, Xiaowei LIU, Bo ZHAO, Minghou XU

Journal Article